|
Hemorrhagic Fever, Ebola
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
A fluorine nuclear magnetic resonance (<sup>19</sup>F-NMR)-based method is employed to assess the binding preferences and interaction details of a library of synthetic fluorinated monosaccharides towards dendritic cell-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN), a lectin of biomedical interest, which is involved in different viral infections, including HIV and Ebola, and is able to recognize a variety of self- and non-self-glycans.
|
31242623 |
2019 |
|
Severe Dengue
|
0.050 |
GeneticVariation
|
disease |
BEFREE |
<i>Conclusions</i>: Dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin (<i>DC-SIGN</i>) promoter-336G/A (<i>rs4804803</i>) polymorphism is association with severe dengue, and it acts in different directions for Asians and South-central Americans.
|
31027310 |
2019 |
|
Paracoccidioidomycosis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Our data indicate that VDR and DC-SIGN genetics variations are related to the susceptibility of oral PCM in the group of patients analysed.
|
30367528 |
2019 |
|
Tuberculosis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Here, we explored DC-specific-ICAM3-grabbing-nonintegrin (DC-SIGN) targeting as a potential vaccine against tuberculosis.
|
29662482 |
2018 |
|
Hepatitis C
|
0.060 |
Biomarker
|
disease |
BEFREE |
DC-SIGN promoter SNPs correlated with risk of HCV acquisition via sexual but not IDU exposure, likely through modulation of mRNA expression levels.
|
29140443 |
2018 |
|
Dengue Fever
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
A common CD209-336G/A (rs4804803) polymorphism in DC-SIGN may affect severity of dengue virus infection (DEN) and incidence of dengue fever (DF) or the more severe dengue hemorrhagic fever (DHF).
|
29054571 |
2018 |
|
Severe Dengue
|
0.050 |
GeneticVariation
|
disease |
BEFREE |
A common CD209-336G/A (rs4804803) polymorphism in DC-SIGN may affect severity of dengue virus infection (DEN) and incidence of dengue fever (DF) or the more severe dengue hemorrhagic fever (DHF).
|
29054571 |
2018 |
|
Tick-Borne Encephalitis
|
0.030 |
GeneticVariation
|
disease |
BEFREE |
<b>Conclusions </b> SNP rs2287886 CD 209 AG heterozygotes predispose humans to develop TBE.
|
28894041 |
2017 |
|
Gestational Diabetes
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
FACS and immune staining showed that, indeed, M2 markers, such as CD206 and CD209, are increased in HBCs isolated from GDM placentae.
|
28824621 |
2017 |
|
Influenza A
|
0.010 |
Biomarker
|
disease |
BEFREE |
Dendritic cell-specific intercellular adhesion molecule-3 grabbing non-integrin (DC-SIGN) has been proposed as an alternative receptor for influenza A(H1N1)pdm09 virus.
|
28493491 |
2017 |
|
Arthritis
|
0.010 |
Biomarker
|
disease |
BEFREE |
The Correlation of CD206, CD209, and Disease Severity in Behçet's Disease with Arthritis.
|
28377641 |
2017 |
|
Behcet Syndrome
|
0.010 |
Biomarker
|
disease |
BEFREE |
The Correlation of CD206, CD209, and Disease Severity in Behçet's Disease with Arthritis.
|
28377641 |
2017 |
|
Dengue Fever
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin (DC-SIGN), a C-type lectin expressed on the plasma membrane by human immature dendritic cells, is a receptor for numerous viruses including Ebola, SARS and dengue.
|
28128492 |
2017 |
|
Hemorrhagic Fever, Ebola
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
Dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin (DC-SIGN), a C-type lectin expressed on the plasma membrane by human immature dendritic cells, is a receptor for numerous viruses including Ebola, SARS and dengue.
|
28128492 |
2017 |
|
Hepatitis C
|
0.060 |
GeneticVariation
|
disease |
BEFREE |
The objective of this study is to evaluate the association of CD209 promoter haplotypes with risk of HIV-1 infection in a cohort of Spanish male intravenous drug users (IDU) infected with hepatitis C virus (HCV) and to characterize the phenotypic effects of the associated variants.
|
27539513 |
2016 |
|
HIV-1 infection
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
We genotyped 4 SNPs of CD209 promoter in 295 HCV males exposed to HIV-1 infection by IDU, 165 HIV-1-infected and 130 exposed uninfected (EUI) and 142 healthy controls (HC).
|
27539513 |
2016 |
|
Hepatitis C
|
0.060 |
GeneticVariation
|
disease |
BEFREE |
In conclusion, CD209 polymorphisms could play a role in the susceptibility to HCV infection as well as interferon treatment response in our study population from North-East of Italy.
|
27348632 |
2016 |
|
Tuberculosis, Pulmonary
|
0.360 |
GeneticVariation
|
disease |
BEFREE |
The PubMed, SCI and Elsevier were searched up to April 18, 2015 for studies on the association of CD209 gene polymorphisms and pulmonary tuberculosis.
|
26722430 |
2015 |
|
Lupus Erythematosus, Discoid
|
0.010 |
Biomarker
|
disease |
BEFREE |
However, double immunofluorescence studies of CD163+ macrophages revealed minor co-expression of M1 (CXCL10, tumor necrosis factor-alpha, and CD127) and M2 (CD209 and transforming growth factor-beta) macrophage-related proteins in DLE skin.
|
26568320 |
2015 |
|
Dengue Fever
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
This study was undertaken to determine the prevalence of dengue clinical symptom persistence during 60days of disease follow up, in patients of Espírito Santo state (ES)-Brazil and to evaluate the relation of single nucleotide polymorphisms (SNPs) in FcγRIIa, CD209, VDR, TNF-α, IL-4, IL-6 and IFN-γ genes with symptom persistence.
|
26429310 |
2015 |
|
Chikungunya Fever
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
The present study suggests that rs4804803 GG genotype of CD209 gene is associated with susceptibility to CHIKV infection.
|
26398832 |
2016 |
|
Alzheimer's Disease
|
0.010 |
Biomarker
|
disease |
BEFREE |
TMEM119-positive microglia did not consistently express polarized markers for M1 (CD80) or M2 (CD163, CD209) in AD brains.
|
26250788 |
2016 |
|
Fungal keratitis
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
The present study evaluated the associations between Dectin-1 and DC-SIGN gene single nucleotide polymorphisms (SNPs) and susceptibility to fungal keratitis (FK) in the northern Han Chinese population.
|
25883525 |
2015 |
|
Cytomegalovirus Infections
|
0.010 |
GeneticVariation
|
group |
BEFREE |
In conclusion, specific SNPs in IL28B, TLR9 and DC-SIGN genes may play a role in modulating the susceptibility to CMV infection in CMV-seropositive KT recipients.
|
25777542 |
2015 |
|
Neoplasm Metastasis
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
By applying the in vivo hypoxia model, the results suggest that intermittent hypoxia significantly promotes the metastasis of Lewis lung carcinoma (LLC), accompanied with more CD209+ macrophages infiltrated in primary tumor tissue.
|
25313135 |
2014 |